A study published in 2012 found that a monsanto gm rounduptolerant maize and very low levels of the roundup herbicide it was engineered to be grown with caused severe organ damage and hormonal disruption in rats fed over a longterm period of two years. Gm food crops are authorized on the basis of short a maximum of 90days feeding studies, usually carried out in rats. In 2004, scientists employed by monsanto had published a paper in the journal food and chemical toxicology fct describing a feeding trial of monsantos gm maize nk603. Nk603 is variety of maize that has been genetically modified gm to confer tolerance to glyphosatebased herbicides gbh. Metabolomics identified 692 and 673 metabolites in kidney and liver, respectively. Joining together to say that the gmo emperor has no clothes empowers citizens to. First published by food and chemical toxicology in september 2012, the article presented a twoyear feeding study in rats, and reported an increase in tumors among rats fed genetically modified corn and the herbicide. Seralini s study is the only longterm study on the commercialized gm maize nk603 and the pesticide roundup it is designed to be grown with. Glyphosate tolerant genetically modified gm maize nk603 was. Another three groups received three different concentrations. The nk603 maize has been engineered to express a modified version of the agrobacterium tumefaciens strain epspscp432. After several months of consumption of an rtolerant soy. Ten things you need to know about the seralini study gmo. Seralini why new studies on gmos showing no harm are.
Long term toxicity of a roundup herbicide a, s x espla and received 11 april 2012 accepted 2 august 2012 available online 19 september 2012 with or without roundup, and roundup alone from 0. Gmo seralini is a onestop resource for information about the research of gilleseric seralini and colleagues on genetically modified foods and roundup. The herbicide tolerant gene, or trait, is the bedrock of the global. The gm maize alone was tested on three groups at 11%, 22% and 33% of the total diet. Seralini s 2012 study1 tested the longterm effects of monsantos gm nk603 maize, which is engineered to survive being sprayed with roundup herbicide, and roundup. Followup on controversial gm maize study by seralini et al. The health effects of a rounduptolerant nk603 genetically modified gm maize from 11% in the diet, cultivated with or without roundup application and roundup alone from 0. Long term toxicity of a roundup herbicide and a rounduptolerant genetically modi. In a study published in food and chemical toxicology researchers led by gilleseric seralini from criigen have found that rats fed on a diet containing nk603 roundup tolerant gm maize or given water containing roundup, at levels permitted in drinking water and gm crops in the us, developed cancers faster and died earlier than rats fed on a standard diet. European studies disprove seralinis gmo maize tumor. Our molecular profiling results show that nk603 and its isogenic control are not substantially equivalent. Most criticisms of seralini s study wrongly assume it was a badly designed cancer study. And like the child who speaks up, are proclaiming what the emperor is telling us is not true. This is the first part of a response by gmwatch to the science media centres expert reaction to seralini s study on gm maize.
The rats that consumed nk603 gm maize andor roundup in prof seralini s trial had an incidence of tumours, which was not just significantly greater than the control rats but also also significantly greater than observed in previous studies of sd rats. Our study is the first and to date the only attempt to follow up monsantos investigation and to determine whether the differences found in the nk603 gm maizefed rats, especially with respect to liver and kidney function, were not biologically meaningful, as. Changes in gene expression were not reflective of liver and kidney toxic effects. Gilleseric seralini, institute of biology, ea 2608, university of caen. Seralini calls for retraction of biased eu study on gm maize. The health effects of a rounduptolerant nk603 genetically modified. Summary the biotech industry has launched an extensive offensive to discredit the study published last september by a team of french researchers suggesting serious concerns about the long term health impact of monsantos nk603 maize and the roundup herbicide it has been genetically engineered. An integrated multiomics analysis of the nk603 rounduptolerant gm maize reveals metabolism disturbances caused by the transformation process. On detourne des fonds publics pour discrediter mes. Maize in groups 14 was grown at field test sites in ohio during 1999, while the reference maizes. The diets comprised 11 percent, 22 percent and 33 percent genetically modified corn nk603 and the rest standard laboratory rat food.
The study used 200 rats divided into ten groups, each of ten males and ten females. Long term toxicity of a roundup herbicide and a roundup. In that brief, abne clearly articulated views by experts and competent national and international food safety authorities on the study, all of which concluded that the study is seriously flawed in many. Transcriptomics showed no segregation of nk603 maize and control feed groups with false discovery rates ranging from 43 to 83% at a cut.
Devoilee par le figaro ce mercredi 4 juillet, letude en pdf. The gmo emperor has no clothes the rights of nature. Three groups of each sex were fed with nk603 maize in concentrations of 11%, 22% and 33% respectively. Roundup is a socalled broadspectrum herbicide that in principle kills all plants. The health effects of a rounduptolerant genetically modified maize from 11% in the diet, cultivated with or without roundup, and roundup alone from 0. What are some of the lessons that journal editors can draw from this episode.
This gm maize is commonly referred to by its trade name, roundup ready maize. Roundup application over a 2year period seralini et al. The efsa has since published monsantos safety data on nk603 maize, but not on glyphosate. Six months or nine monthslong studies are not enough to show long term effects on health of gmos or of any pesticide they contain, like roundup for the gm tolerant soybean. The incredible seralini affair hello dear reader, in this installment i want to share with you something i have written on one of the most shocking corruption scandals in the history of a very corrupt european union commission together with corruption by monsanto and the related gmo agribusiness industry. Relationship between faecal microbiota and plasma metabolome in.
A total of 200 sd rats were used for the study, 100 of each sex, divided into groups of ten. However, there was no longterm toxicological assessment for nk603, or for roundup. Faqs on seralini s gm nk603 maize and roundup study. The remaining 89, 78 and 67% of the diet comprised standard, commercially available laboratory rat food made by the firm safe. Nk603 est le nom dun caractere genetique tolerance a lherbicide glyphosate. Seraliniarjopluralityopinionscientificdiscourseseralini20. The efsa had previously assessed nk603, and glyphosate, the declared active principle of roundup, as safe on the basis of regulatory data, which they never fully published. By contrast, the differences between the nk603 maize sprayed with roundup and the unsprayed nk603 maize are mostly due to the composition of the metabolome since the latest has a high weight on the vertical axis red and black dots of the pseudoeigenvalues space. Long term toxicity of a roundup herbicide and a rounduptolerant genetically modified maize. The nk603 data are in a pdf format preventing an easy statistical reanalysis. From thesethree cultivations of maize, laboratory rat chow was made based on the. In thissense, eseu aims to enable rational discussions dealing with the article from g.
Submitted by food democracy now on november 28, 20 2. A scientific analysis of the rat study conducted by gilles. It was a chronic toxicity study and a welldesigned and wellconducted one. Glyphosate tolerant genetically modified gm maize nk603 was assessed as substantially equivalent to its isogenic counterpart by a. Seralini about toxicity and carcinogenicity of glyphosate for rats at low dose are correct. Feeding study in rats with genetically modified nk603. French academies of science, monsanto, seralini and nk603. Our study is the first and to date the only attempt to follow up monsantos investigation and to determine whether the differences found in the nk603 gm maize fed rats, especially with respect to. Monsantos study was a 90day rat feeding trial on nk603. Three of these groups received the gm maize nk603 one test group each with 11, 22 and 33% maize in the standard diet and three received gm maize nk603 treated with roundup one test group each with 11, 22 and 33% maize in the standard diet.
A diet that partially comprised genetically modified nk603 maize in which he tested three different proportions. The danish national food institutes assessment of a new. The gmo emperor has no clothes citizens around the world can see the false promises and failures of gmos. The gm maize alone was tested on three groups at 11%. An integrated multiomics analysis of the nk603 roundup. Moreover, we demonstrated in several studies 810 that roundup is far more toxic than glyphosate because of noninert adjuvants. Pdf a comparison of the effects of three gm corn varieties on. However, there was no longterm toxicological assessment for nk603. Seralini et al found that a gm maize and its associated herbicide.
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